supercres.net

CA1 pyramidal cell tattoo

admin — Mon, 10 Oct 2011 20:03:01 +0000

(This one isn’t really a project, but I hope you’ll bear with me.)

In August 2009 I got my first tattoo: an image of a reconstruction of a pyramidal neuron from area CA1 of the rat hippocampus. The reconstruction is taken from the paper:

Nace L Golding, Timothy J Mickus, Yael Katz, William L Kath, and Nelson Spruston. Factors mediating powerful voltage attenuation along CA1 pyramidal neuron dendrites. J Physiol October 1, 2005 568 (1) 69-82.

The paper can be found here. Dr Spruston provided more info about the model:

Scientifically, it’s one of three CA1 cells we reconstructed in detail after recording simultaneously from the soma and a dendrite. The recordings (performed by Nace Golding) were technically very diffcult and the reconstructions took several hours of tedious and careful work. The experiments provided data that constrained the model and provided more information about the basic properties of the neurons. Subsequently, the models have been really helpful in making predictions that led to new experimental discoveries.

I submitted my tattoo to Carl Zimmer’s excellent Science Tattoo Emporium, which was part of my inspiration for the venture. It was published here on August 15th, 2009.

On November 1, 2011, a fleshed-out version of the blog post appeared in Zimmer’s book Science Ink: Tattoos of the Science Obsessed (Amazon link). My page can be seen here:

TMS-ERP endophenotypes in schizophrenia

admin — Fri, 07 Oct 2011 21:35:54 +0000

Using TMS-evoked potentials to probe neural response mechanisms in schizophrenia.

With Bruce Turetsky, MD and Mahendra Bhati, MD.

Presented at ICOSR 2009 by B. Turetsky.

More info coming soon.

Real-time MATLAB implementation of algorithm for DBS electrode placement

admin — Thu, 06 Oct 2011 02:42:01 +0000

Senior design project at University of Pennsylvania, School of Engineering and Applied Science.

Real-time MATLAB implementation of functional localization and visualization of the STN from microelectrode recordings acquired during DBS surgery with unsupervised machine learning.

With Charles Li and John Paulett; advised by Stephen Wong, MD, Shabbar Danish, MD, and Leif Finkel, MD, Ph.D.

Patrick Crutchley, Charles Li and John Paulett, April 2007, Philadelphia, PA

Winner, Bioengineering Department Senior Design Award.

Published in Journal of Neural Engingeering: Wong et al., 2009.

More info coming soon.

PyEPL implementation of WMS/CVLT

admin — Thu, 06 Oct 2011 02:34:47 +0000

Porting standardized tests of memory, mood, and personality into Python-based Experiment Programming Library (PyEPL: Geller et al. 2007; publication, project page) in support of project Individual differences in free recall.

Tests included:

Wechsler Memory Scale
California Verbal Learning Test
NEO-FFI
PANAS-X
SDFMS
SWLS
PSWQ

Personality/mood tests (3-7) used code written by Jonathan Miller.

More info coming soon.

Brain morphology endophenotypes in schizophrenia

admin — Wed, 05 Oct 2011 22:47:06 +0000

Placeholder.

More info soon…

Individual differences in free recall

admin — Wed, 05 Oct 2011 22:29:57 +0000

Placeholder.

More info coming soon…

Whoops!

admin — Wed, 05 Oct 2011 19:22:55 +0000

If you’re seeing this in your RSS reader, it’s because you still have my old feed bookmarked there.

This particular feed will turn into a feed of projects I’ve been working on or have worked on in the past. I obviously haven’t updated the blog with new posts in a while, but if/when I do, they’ll show up in the feed

supercres.net/blog/feed

But you should totally stick around here if you want to hear about projects I’ve been working on. Super-exciting stuff. (Not really.)